Synthesis of cyclopropyl-substituted furans by brønsted Acid promoted cascade reactions.
نویسندگان
چکیده
Chloroacetic acid promotes an efficient and diastereoselective intramolecular cascade reaction of electron-deficient ynenones to deliver products featuring a 2,3,5-trisubstituted furan bearing a fused cyclopropyl substituent at the 5-position. Synthetically relevant polycyclic building blocks featuring rings of various sizes and heteroatoms have been synthesized in high yield using this mild acid-catalyzed reaction.
منابع مشابه
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ورودعنوان ژورنال:
- Angewandte Chemie
دوره 54 19 شماره
صفحات -
تاریخ انتشار 2015